Course Description
Theoretical Course
1. Structure and geometry of organic molecules. Isomerism. Geometric isomerism and stereoisomerism. Chirality and optical activity. Racemic mixtures.
2. Nomenclature of organic molecules. Carbon chains and heteroatoms. Homologous series and functional groups (hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids, esters, amines, amino acids, lipids. Aromatic compounds and aromatic character. Terpenic compounds).
3. Electronic structure of organic molecules. Hybridization: sp3, sp2 and sp. Sigma bonding and saturated compounds. Unsaturation; π-bonding in double and triple bonds. π and π* molecular orbitals in unsaturated organic compounds. Molecular energy levels. Structure of molecules and their physical and spectroscopic properties in the ultraviolet / visible. Chromophore groups. Electronic transitions (σ àπ* and πà π*). Structural features of colored compounds: organic pigments, dyes. Luminescence.
4. Chemical reactions of organic molecules. Substitution, addition and elimination reactions. Oxidation of organic compounds. Mechanisms of organic reactions. Electrophilic and nucleophilic reactions. Free radicals and homolytic reactions. Reaction rates and temperature effect. Arrhenius law. Mechanisms of reactions (chain reactions, polymerization, catalysis, enzyme catalysis).
5. Macromolecules – biomolecules. Proteins, lipids and carbohydrates; polysaccharides. Synthetic polymers and resins. Polymerization reactions. Properties of polymers.
Course Practicals
N/A
Course Aims and Objectives
Course aims
To understand the structure of carbon compounds; how they form molecules, nomenclature and some basic physical and chemical properties.
Course objectives
The students are expected to be familiar with organic chemical structures and correlate these, and their properties, with those of routinely encountered materials; to deal with issues and questions related to stereochemistry and chemical reactivity.
STUDENT PERFORMANCE EVALUATION
Language of evaluation: Greek Student evaluation (100%): written exam (questions demanding short succinct answers; multiple choice questions; open ended questions)
ATTACHED BIBLIOGRAPHY GREEK McMurry, John, Οργανική Χημεία, Πανεπιστημιακές Εκδόσεις Κρήτης, (2 τόμοι), 1998. Klein, David, Οργανική Χημεία για τις Επιστήμες της Ζωής, UTOPIA Εκδόσεις ΕΠΕ, 2015 Βάρβογλης, Α., Επίτομη Οργανική Χημεία, εκδόσεις Ζήτη, 2005. Χαμηλάκης Στυλιανός, Οργανική Χημεία, Ελληνικά Ακαδημαϊκά Ηλεκτρονικά Συγγράμματα και Βοηθήματα – Αποθετήριο “Κάλλιπος”, 2016 Μαυρομούστακος Θ., Τσέλιος Θ., Παπακωνσταντίνου Κ., Θεμελιώδεις Αρχές Οργανικής Χημείας, Εκδ. Σ.ΑΘΑΝΑΣΟΠΟΥΛΟΣ & ΣΙΑ Ο.Ε., 2014 Vollhardt Peter, Schore Neil, Οργανική Χημεία, τόμοι Α΄και Β΄, Εκδ. Αδελφών Κυριακίδη Α.Ε., 2012 Meislich Herbert, Neckamkin Howard, Sharefkin Jacob, Οργανική Χημεία, 3η Έκδοση, Εκδ. Τζιόλα και Υιοί, Α.Ε., 2001 WadeJ. R., Οργανική Χημεία, 7η Έκδοση, Εκδ. Τζιόλα και Υιοί, Α.Ε., 2011 ENGLISH J. March, Advanced Organic Chemistry, 6th Edition, Wile Smith, J. Gorzynski, Organic Chemistry, 3rd Edition, McGraw-Hill, 2011y, 2007